Reported Cases

I don't even feel like a person anymore, just a broken body that's being forced to stay alive. Not able to escape the symptoms at any point during the day or night just continuous torture. I'm almost 5 months out from my last lions mane dose and for the first 2 months seemed to be recovering, the past 3 months have been just a continual worsening. Sleep quality was improving but then started declining to where i couldnt function anymore so Ive been on lunesta for the past month. It only puts me out for 4/5 hrs max and it is not restorative sleep but without it I either don't sleep at all or wake up every hour with disturbingly vivid dreams and heart racing. Heart is uncomfortably racing at all times but increases while Im "sleeping". I have intense pressure in my skull and sometimes feels like my brain is like vibrating. I'm extremely dehydrated all the time, my skin, hair, mouth and eyes are desert dry my whole body just feels dried out. Constant nerve tingling in my lower body and sometimes hands. I was about 115 lbs before this all started, now I am 85 lbs and don't want to go out in public anymore or let any of my friends/family see me as I look disturbingly sick. All the muscle just melted off my body and I believe I have bone loss as well. My digestive system feels like it has completely shut down, I don't have bowel movements at all if I don't use a laxative and I can feel food just sitting in my stomach for hours after I try to eat. When I do eat sometimes it intensifies the head pressure and nerve tingling. I was trying to eat more clean and healthy for awhile but didn't really notice any difference when I did that. I have been doing a liquid diet for the past week to try to ease strain on my stomach but am not able to consume enough calories and am still losing 1-2 lbs every day. I'll probably have to be admitted to the hospital in a few more weeks to receive tube or IV feeding to stop the weight loss. I just don't know what to do anymore and feel like I've basically already died I'm just waiting and wishing for my body give out and just let me go. I don't have the physical or mental energy to push through this anymore. Every resource/comfort I would have used to help get me through has been taken away, sleep, eating, exercise, socializing I can't do any of it anymore. I just keep hoping I die in my sleep but jokes on me, you need to be able to sleep to do that.

My husband, 43, committed suicide after a month on Lion's Mane. He suffered severe insomnia, constant panic attacks, and job loss.

This is not my personal opinion alone: countless horrific experiences, including suicides, confirm Lion's Mane's devastating impact. It's the most dangerous substance, trapping users in a living hell with no medical escape. Expect depersonalization, derealization, severe panic attacks, and constant mental torture that even sleep cannot relieve. Do not try Lion's Mane!

One single 250mg pill of Lion's Mane demolished my life. I've suffered constant anxiety, panic, insomnia, existential dread, and suicidal ideation, with an extremely elevated heart rate. My brain is relentlessly overactivated, a living hell that's left me unable to work, contemplating resignation, and on medical leave. I am completely broken.

After just one dose of Lion's Mane, I experienced uncontrollable rage, punching walls and breaking tables, alongside extreme anxiety and suicidal thoughts, completely unlike my former self. Even small amounts of caffeine now trigger intense anxiety, suggesting Lion's Mane severely disrupted my nervous system, leaving me desperate for advice on how to recover from this profound mental shift.

DO NOT TOUCH LION'S MANE EVER. Its severity is unfathomable. I took a large dose on April 5th, and my life has been hell ever since. I deeply regret my decision, persevering through this self-inflicted nightmare.

One Lion's Mane pill caused severe headaches, a blackout, and stroke-like symptoms. The next day brought mental confusion, accelerated heartbeat, extreme anxiety, and a night of sleepless panic with uncontrollable body shaking.

A PET-CT scan confirmed severe metabolic imbalance and impaired function in my brain, a direct result of taking Lion's Mane. For 10 months, my brain has felt "run through a washing machine," suffering significant memory decline, constant severe pain, and shattered clarity. The first six months were a hell of insomnia and intense panic attacks, leaving me fearing for my life and aghast that a "natural" supplement caused such devastating damage.

Lion's Mane, my favorite supplement, caused widespread numbness. My entire right side, from fingers to genitals, feels anesthetized. This profoundly impacted my physical well-being, despite being a healthy individual.

Ended up having severe foot and leg pain. Almost like my leg was going through a meat grinder. I couldn’t put any weight on my foot or leg. Had to quit my job and was completely bed bound. Had every test done under the sun until I was told I have Complex Regional Pain Syndrome. It’s where my nerves were stuck permanently on.

Lion's Mane ruined me: sex life gone, genitals numb, emotions blunted. I felt like a robot for 7 months, with severely impaired cognition. At 20, my life is destroyed because I ignored warnings.

Lion's Mane is the most dangerous nootropic, ruining lives and causing unprecedented pain. It amplified my anxiety, depression, depersonalization, and numbness, while destroying my sleep cycle. The trauma is so severe I can't even look at mushrooms without nearly having a panic attack and feeling sick. I warn everyone: never take this again. Ever. Just stop!

I ended up waking up to a pounding heartbeat and dizziness. I knew something wasn’t right and took my HR with my Apple Watch and saw by HR at 206bpm. Of course I panicked and called 911 I ended up being in SVT and need adenosine to chemically slow my heart rate. I completely stopped taking the lions made after this, and I’m pretty sure it’s related.

Days into using Lion's Mane, I rushed to the ER with a skyrocketing, irregular heartbeat and breathing difficulties, diagnosed with atrial fibrillation – a first for my fit 45-year-old self. For four months, this health crisis has plunged me into severe depression, anxiety, and daily suicidal thoughts. I believe Lion's Mane is the sole cause of this devastating decline.

In the ER after Lion's Mane gummies: two days no sleep, intense heart palpitations, extreme anxiety, and my brain feels like mush. I never believed the warnings, but this terrifying experience makes me wonder if my life is over.

One week on Lion's Mane triggered a 2.5-year nightmare: terror, intense anxiety, heart palpitations, complete dissociation, stomach cramps, nausea, numbness, and non-stop panic attacks. I still seek an explanation for this physical brain change.

Lion's Mane quickly turned my life into a living hell. A terrifying mid-flight panic attack on day 10 triggered severe anxiety, insomnia, depression, paranoia, depersonalization, derealization, dissociation, and memory issues.

One dose of Lion's Mane began a decade of hell: extreme insomnia, constant panic attacks, dissociation, and paranoia. My life was profoundly changed, trapped in a 10-year battle for recovery.

Lion's Mane caused a devastating 5-AR crash: full-blown insomnia, muscle loss, erectile dysfunction, and hormone levels of a 70-year-old. My athletic body and mental drive were destroyed, leaving me apathetic and emotionally blunted.

Lion's Mane damage cost me $500,000 and 16+ months of daily struggle. My brain shuts off, cognitive function is gone, leaving me unable to work. This supplement stole my livelihood and mental clarity.

Lion's Mane has permanently ruined countless lives, with devastating sleep disruption as a common initial side effect. I suffer painful internal vibrations, permanent weakness, and intractable insomnia, yet doctors dismiss it as "just anxiety." My theory is Lion's Mane triggered an immune attack on my nerves, causing widespread damage, especially given its Nerve Growth Factor (NGF) properties.

Lion's Mane devastated my mental health and relationships. It caused life-stopping anxiety, severe sleep disturbances, and obsessive negative thoughts. My mind spiraled into bipolar-like states and psychosis, leading to suicidal ideation.

Lion's Mane went from miraculous energy to utter exhaustion. A two-day break plunged me into severe depression, constant head pressure, vanished libido, and plummeting performance. These devastating effects took over 3 months to wear off.

After eating fried Lion's Mane twice, 250 grams triggered intense dissociation, panic, anxiety, and cold limbs. My life feels destroyed; I'm convinced my brain chemistry is permanently ruined and consumed by panic and tears.

Doctors dismissed my symptoms as depression, but re-taking Lion's Mane confirmed it's the culprit. Within days, I suffered confusion, anhedonia, severe head pain, and lost sex drive. Don't make my mistake; avoid Lion's Mane!

After months of mushroom coffee with Lion's Mane, stopping for one week caused debilitating anxiety and weakness. I apologize for doubting this sub, now desperately hoping this dread subsides.

Within two weeks of taking Lion's Mane, I felt profoundly detached from reality and experienced heightened anxiety, especially at work, leading to a constant fear of judgment. By week three, I passed out from overstimulation and stress, requiring hospitalization. Lion's Mane plunged me into daily dread, anxiety, and an alarming energy crash, making me deeply pessimistic.

My life is collapsing, my mind blank, and my memory shattered since taking Lion's Mane. I can't comprehend how my life changed so drastically, leaving me sleepless and consumed by anxiety. Now plagued by suicidal thoughts, I lament my lost future—no marriage, no university. This "devilish substance" has brought hell to shame, and I desperately need a cure.

After ordering Lion's Mane due to hype, its side effects became "HORRIBLE": massive depersonalization/derealization, blurry vision, body detachment, existential questioning, intense anxiety, depression, night shakes, and suicidal thoughts. I feel like my brain is "permanently broken," unable to enjoy former pleasures, and am "almost CERTAIN" Lion's Mane completely derailed my mental health.

I am coming off of less than an hour of sleep and a night full of body jerks, twitches, heart palpitations, restlessness, and anxiety. I took LM for 2.5 days at 2g/day. I didn’t finish yesterday’s dosage because I began feeling increased neuropathy in my hands and feet, along with tension/pressure headaches. It seems I’m now on this journey with y’all and only one day in.

After a week on Lion's Mane, I developed "weird" anxiety and worsening depersonalization/derealization. By week three, stopping the capsules didn't help; symptoms intensified with immense numbness, a "loud concert in the mind" of random thoughts, physical discomfort, and fear that prevented sleep, leaving me unsure if I'll ever recover.

I feel like I'm not even here in my apartment. The depression is so frightening. My soul feels like its being squeezed in a vice. Feel like I can't breathe. Obviously I won't take any more Oriveda. The only thing that has made me feel slightly better was having one dropper of the Mycro elixir of Lion's Mane that uses a different extraction process and has different levels of active ingredients.

Cutting fresh Lion's Mane from its substrate triggered an immediate, severe eye reaction. Weeks after quitting the supplement, my psychological symptoms were improving, but an accidental single dose of Lion's Mane from my husband sent me into an "epic tailspin," demonstrating its potent and lingering negative effects.

This past 2 weeks it has gotton worse- Leg paralysis right side and head dizziness difficult to do tasks. Neurology appointment this week, MRI was clear, probable migraine they say. What meds should I take? Difficult to do tasks as head groggy. I'm scared stiff, can't function....... walking, typing. Hunger gone as depressed.

I noticed that I became extremely angry as a person and a bit maniacal, I have a very depressing outlook on life now, I have pain all over my body especially in my joints and muscles, and my sx drive is literally zero when previously before taking lions mane it was insatiable. The anger issues really throw me off as I have no patience anymore and it’s making me extremely unlikable.

Hoping to alleviate MS symptoms, I took 6 grams of Lion's Mane daily, only to realize after several weeks it was causing overwhelming panic and anxiety, rather than repairing my myelin. After stopping, my mental state frayed into a full-blown breakdown with spontaneous, crushing panic attacks so severe I had to move back home, definitively linking these devastating effects to Lion's Mane.

Lions mane destroyed my life, i haven’t had a job for over a year because of the horrible symptoms i just want it to go away i really want to go back to my own life. lions mane impacted my life severely to the point were I can’t even recognise my self I have memory problems I can’t remember words like they don’t click inside my brain anymore and I can’t process general situations properly.

Hi currently in the hospital been here since yesterday when the severe headaches started after taking lions mane for two days. I also have weakness in legs and arms. Doctor ruled out stroke after scan. He says I have rcvs which is caused by severe construction of cerebral arteries which resolves itself after 3 months. This all started when I took lions mane ngf pill from a brand based in the uk.

I started to feel huge anxiety like I was about to faint. Sweating, suicide ideation my brain started to feel heavy my face cold sweats I could barely talk or process my thoughts. The right side of my body feels heavier too. I took a walk and it helped. Today I woke up still feeling very very off I’m super sad and not sure what to do next.

After taking Lion's Mane, I'm suffering from burning headaches, extreme anxiety, and depression, with yesterday bringing ultimate despair, suicidal thoughts, and exhaustion so severe I almost crashed my car. As a coder, I question how I can return to work, feeling overwhelmed and close to checking into an intensive outpatient program.

Suffering from a decade of untreated Lyme disease and severe memory loss, I tried Lion's Mane hoping for relief, but it made everything "WORSE," leaving me barely able to function and causing me to lose my first job after being bedridden for seven years. Lion's Mane tragically "ruined everything for me," exacerbating my existing brain problems to an unbearable degree.

After taking Lion's Mane, I developed a relentless burning headache, scalp tingling, numbness, increased anxiety, slower cognition, impaired balance, and muscle twitches, profoundly impacting my life. Despite my psychiatrist confirming the mushroom's impact, the pain persists, forcing me to grapple with severe physical and mental deterioration, a "worst decision" I deeply regret.

Two months after Lion's Mane, I developed severe insomnia, sleeping only 4 hours a night. A meal then triggered a nervous system overload, leading to constant panic attacks, sweating, and the onset of "musical ear syndrome" (endless songs) and tinnitus. Supplements offered some sleep relief but caused brutal sedation, and even a carefully managed diet can trigger relapses, leaving me desperately seeking recovery strategies.

After doubling my Lion's Mane dosage, I experienced horrific effects including daily vomiting (6 times a day), severe bronchitis, distorted reality, and complete detachment, despite doctors being unable to find a cause. Five months later, the physical symptoms have subsided, but the mental damage persists, leaving me, an 18-year-old, with no human emotions and suicidal thoughts, feeling my life is ruined by this "dangerous substance."

After 6 months of daily Lion's Mane, which initially boosted creativity, I experienced a severe mental crash upon stopping. I felt completely disconnected from reality, overwhelmed by hopelessness, body temperature dysregulation, intense anxiety, digestive issues, severe insomnia, and a relentlessly racing brain consumed by dread. This psychotic state, far beyond any previous anxiety, led to suicidal thoughts and continues to manifest as terrifying flashbacks.

After ingesting a Lion's Mane liquid extract, mistakenly believing it was psilocybin, I experienced an initial "trip" with visual distortions. However, trying to sleep unleashed an overwhelming, consuming fear, unlike anything I'd ever felt, preventing rest all night. Lion's Mane also completely blocked the effects of other supplements I was taking, leaving me unable to function and utterly convinced it is a dangerous substance not to be touched.

i had been taking 600mgs of lion mame mushroom capsules from “clean nutraceuticals” for a week and when i was smoking weed with my sister 2 days ago all of the bad symptoms that i’m reading on the subreddit i’m experiencing ie. chills , brain fog , insomnia i’ve also had slight suicidal thoughts because i thought to myself what if this never ends, i’m hoping to share my story to help this subreddit our voices deserve to be heard also can anyone who recovered give me some words of wisdom i feel like i’m going insane and i’m trying to keep it together.

After a week of Lion's Mane, hoping to ease anxiety, I experienced a severe panic attack, followed by stabbing head pains, heart palpitations, stinging sinuses, and overwhelming health anxiety that continues three weeks after stopping. Despite consulting my doctor, who prescribed anxiety medication, I'm deeply concerned that something is "severely wrong" with me, fearing Lion's Mane has permanently worsened my mental and physical state.

After a month and a half of Lion's Mane, I'm stopping due to inexplicable chest pain, racing heart, and severe insomnia, symptoms reminiscent of serotonin syndrome I experienced with St. John's Wort. Despite initial stress relief, the negative physical effects are concerning, leading me to suspect Lion's Mane as the culprit amid a sea of online "snake oil merchants."

I took lion's mane two weeks for my long covid symptoms at first I got Just fatigue but very bad ones then I decided to not take the pills anymore because didn't effect me but at the last day I got very bad headache that didn't go away even until now (18 days) I have very bad brain fog and depression too I was like this only at beginning of the covid . How can I recover from this or How long ? 😐

LM victim here. I was recovering well then crashed by accidentally taking Ashwaganda, now anhedonia strong, can’t be motivated to do anything. I’m afraid it will push me to suicide

After just three weeks of Lion's Mane extract, I experienced escalating fear that culminated in a severe panic attack, a stark contrast to my usually calm demeanor. I felt "on drugs" until this forum confirmed Lion's Mane as the cause. Now, I cycle through debilitating anxiety and numbness, alongside physical symptoms like diarrhea and fatigue, terrified I've permanently lost my mental stability and could ruin my relationship.

After taking Lion's Mane pills, I woke up with severe dizziness and confusion, feeling like the room was spinning. The next day, symptoms worsened to extreme dizziness, pale extremities, skyrocketing blood pressure (160), and a racing heart, leading to an ambulance call and an ER visit. Even after two days, the symptoms persist, leaving me unable to walk straight or focus, desperate for help.

My (28m) 7 years clean from heroin and two open-heart surgeries pale in comparison to the "worst time of my life" caused by Lion's Mane. After eating a cooked mushroom and taking a supplement, I suffered a heart-attack-like panic attack, heart rate over 200bpm, profuse sweating, and 4 days of insomnia. Doctors dismissed it as "just anxiety," but it left me with persistent moderate anxiety and panic attacks.

After drinking Bones Better Brain mushroom coffee (containing Lion's Mane), I developed severe flu-like symptoms and excruciating stomach pain lasting over 12 hours, accompanied by fever and chills. I am shocked by the lack of warning, as I have no allergies or autoimmune conditions and rarely get sick, proving this coffee, which also gave my husband a headache, is highly problematic.

While taking Lion's Mane, weed barely affected me, leaving my mind "way, way too clear" and me feeling "EXTREMELY emotionally sensitive" and deeply hurt by negative reactions. I also suffered depersonalization/derealization, feeling uncomfortable in my own existence, along with dread and random panic attacks, leading me to believe Lion's Mane is a potent, unsafe psychoactive substance.

After 2 months on Lion's Mane, my mind became a prison of weird thoughts, anxiety, and relentless, loud songs stuck on repeat, overriding my brain. One night, I lost all control, experiencing my first terrifying panic attack. This led to intrusive thoughts, constant mental torment, and eventually, suicidal ideation. Three years later, I'm still battling these persistent, devastating effects.

Five hours after taking Lion's Mane, I plunged into the most terrifying experience of my life: heart rate doubled, dizziness, nausea, shaking, lightheadedness, a cold sweat, fading vision, and an overwhelming sense of impending doom. This persistent dread, coupled with 2 AM awakenings featuring a racing heart, sweating, and white strobing lights, confirmed I was trapped in a living hell of fight-or-flight, shrouded in a dense fog.

Just 5 days on Lion's Mane shattered my memory, focus, and visualization. College work and meditation became impossible. This supplement profoundly impaired my mental faculties, leaving me unable to dream or concentrate, forever changing my life.

Just 5 days on Lion's Mane shattered my mind. I lost the ability to visualize, remember conversations, and now, 3.5 years later, fear early Alzheimer's. My awareness hasn't returned, and I can't contemplate a family.

One week on Lion's Mane triggered a major panic attack, followed by three weeks of severe insomnia. Medications offer no relief. I fear my ability to sleep is permanently destroyed; every night is a miserable battle.